I was on remeron for close to a year, to me it worked wonders at the time. It helped me with both the anxiety, insomnia and maybe most importantly my OCD. Sure, some people experience bothersome side-effects, but overall remeron seems to be pretty tolerable for most people. I can compare remeron to a quite significant amount of antidepressants, and in my opinion remeron is definitely one of the better depression/anxiety meds.
If you experience side-effects, which you most likely will no matter what meds you take, rest assured that no permanent side-effects has been noted from remeron use.
The only side-effect I experienced initially was tremors in the hand, and some nausea, but they quickly subsided. Overall, I think it's a great med. It had almost the same effect on me as chlomipramin did, but with 70% less side-effects