I am asking this question to see if anyone else taken 50mg of generic zoloft for almost 2 years and made you depressed? My husband was put on this almost 2 years ago for his anxiety,sence then he has not been his "normal self". I am getting scared because I know we are not the same as we once were. Soo much has changed for the both of us sence all of this. I have been wondering this for about a year but just thought it was our life changes but as time goes on thinking it would get back to normal. It hasnt,only not worse but not the same just grr frustrating to see that I know he is just not how he use to be. Anyway....Just wondering if anyone else toke zoloft and it made you depressed. Everything I read has to do with people that are just starting it or have only tried it for a month or so. Any advice would be much appreciated!