I was taking most of these meds prior to 2001 and I can't recall the dosages or the length of time that I was taking them. It seems like I tried them all, even lithium and ECT. ECT was effective and I was put on maintenance ECT it was not very practical since the effects lasted only a week or two. In 2001, I turned the corner when I was put on Clozaril. It really worked well; however, I seemed to be very sensitive to the sedation and I can only take it at nighttime. I had to reduce the dose because it wall extremely difficult to wake up in the morning. I take 2 mg of alprazolam ER in the morning but I am experiencing rebound anxiety at around 5:00 pm when it wears off. I am also taking two 0.5 mg tablets of regular alprazolam. I have difficulty in social situations so I take it during the day (just before I lecture for class). I am looking for something to take at around 5:00 PM when everything wears off. I admit that I need to exercise, but even so, the rebound anxiety can get very intense. Very recently, I may drink a glass or two of wine at around 5:00 pm and it works, but having to drink alcohol as a remedy just does not feel right. Thanks for your reply.