Well today was kind of a disaster, I had major sweating problems last night, felt very anxious when I got up, bp already up but when I got to work (school) I was so keyed up I was working on something with another teacher then forgot my first class. I also had major stomach pains last night which morphed into chest and back pains when I was getting up. Ended up with my friend walking me to the nurse, she took my bp (I was quite upset by this point, a mix of anger, frustration, and teariness) and it was 160/100! Later it came down significantly, but not quite to normal while I was there. Got an emergency apt with my pdoc and was taken there, she told me to up the Pristiq to 100 mg and take more klonopin to keep the pressure down, which she felt was due to anxiety. Other options were to take 5 mg lex on top of it but she didn't think that was a viable solution in her experience, and to consider taking remeron to help with sleep and supplement the activity of the Pristiq. She felt for now the cleanest option was to take more Pristiq b/c it did help initially when I took it while still on lex, and many of her patients take 100 anyway, a few higher. I told her I was scared and really frustrated, but I guess I need to keep trying. If my bp gets nuts I can always go to an emergency room I guess, and it is most likely due to anxiety anyway. A curious thing I noticed is that when I did get emotionally upset, the stomach pain tended to go away, its like this illness seems to find either a physical or mental way to torture me, but not necessarily both at the same time. I also took an extra .25 klonopin in her office, it made me sleepy as I waited for my wife to come get me, and when I got home my bp is still high but not ridiculous. After eating lunch late my stomach seems to have calmed down at least for now, a bit of a headache and eye ache but I am hanging in there. Will try again tomorrow, I have to take both Pristiqs at the same time when I get up. I really hope it works, and I know it might be a few days, she told me of a patient for which 50 did nothing and then that one felt much better on 100 within less than 2 weeks. This stuff is so complicated, I wish there were easy answers.