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Author Topic: Increase of Sertraline(Zoloft)  (Read 1451 times)

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Offline Luisa1974

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Increase of Sertraline(Zoloft)
« on: February 17, 2014, 07:23:15 AM »
Can anyone please help or advised, I have increased my dose of Sertraline from50mg to 100mg for a week now and am starting to fell extremely anxious and can not leave the house.  What I would like to know is, dose an increase of Sertraline cause the same start up symptoms of when first starting out, i.e increased anxiety. Any guidance would be very much appreciated as I am now at the end of my tether!!

Help!
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Offline bababel

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Re: Increase of Sertraline(Zoloft)
« Reply #1 on: February 17, 2014, 08:58:16 AM »
Yes, feeling the start up side effects when increasing your dose is normal. I have increased from 50 to 75 (at 12.5 mg increments) and even with such a small jump I am getting anxiety. I know that in a couple of weeks the side effects will go away though, so I am not that worried.

Did you do a straight jump from 50 to 100? That is a big jump to make at once and would really explain the increase in anxiety.
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Offline Luisa1974

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Re: Increase of Sertraline(Zoloft)
« Reply #2 on: February 17, 2014, 10:49:21 AM »
Hi bababel

Yes I jumped straight to 100 at per my psychiatrist she said going up will not affect you only going down a dose, boy was she wrong, I have been on 100 for a week now and at first I was no different but today omg I feel huge waves of anxiety. How long have you been on your increase for and do you feel like you did when initially started up? Be good to hear as my psychiatrist reckons that you should not get any anxiety ! Yeah right
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Offline bababel

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Re: Increase of Sertraline(Zoloft)
« Reply #3 on: February 17, 2014, 03:02:08 PM »
Yikes, your doctor is very wrong about it not causing anxiety when you increase the dose. Anyone here will tell you it can and almost certainly will, especially with a jump as big as the one you made. I just started 75 mg two days ago. First I was at 25 mg for 10 days, then I went up to 50 mg. The jump from 25 to 50 was TERRIBLE and I had lots and lots of panic and anxiety for a couple of weeks before I finally felt better. Then I had some breakthrough anxiety so my doctor said I could go up to 75 mg. I decided to do it in 12.5 mg increments because I didn't want the same side effects. It has been much better this way.

The extra anxiety you are feeling should go away in a week or two. If you ever do need to increase again though, do yourself a favour and make it smaller increases. A 50 mg increase is huge! In the meantime, were you given a benzo to help you before the SSRI kicks in? I found that I needed a Xanax almost every night when I went from 25 mg to 50 mg because of the extra anxiety.
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Offline Luisa1974

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Re: Increase of Sertraline(Zoloft)
« Reply #4 on: February 18, 2014, 04:39:45 AM »
thanks for your reply bababel, I am into my second week now of the increase and really very anxious and agoraphobic, do you get agoraphobic? she did not give me any benzos and to be honest I don't think I would of taken them anyway I would be scared of getting addicted. it is encouraging to know that your anxiety went after a couple of weeks, maybe I just need to stick it out a bit longer, it just feels I am never going to get better. 

Good luck with your increase, do you think you will increase further? I feel 100mg is too high but I will take anything to get better at the moment, especially as I have two young children to look after! It is really good to talk to someone going through the same as me and I really appreciate your replies.
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Offline insights

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Re: Increase of Sertraline(Zoloft)
« Reply #5 on: February 18, 2014, 05:43:48 AM »
she did not give me any benzos and to be honest I don't think I would of taken them anyway I would be scared of getting addicted

You won't become addicted to benzodiazepines, but when taken regularly for more than a month or so you may become dependent, just as you will to sertraline, and will need to wean off them. However, the anti histamine hydroxyzine (Atarax) has anti anxiety properties and might be just strong enough. It usually does not cause dependence.

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I feel 100mg is too high

Most would be on 100-150mg of Zoloft. The maximum is usually 200mg, or 300mg with medical supervision. It is better to take too much than too little. The brain just ignore any excess, whereas too little can cause neurogenesis to fail.

Ian
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NOTE: I'm not a doctor, and particularly not yours, so there may be factors I'm unaware of. Therefore all advice is of a general nature and you should consult your doctor before following any of it, especially before changing med doses.

Offline bababel

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Re: Increase of Sertraline(Zoloft)
« Reply #6 on: February 18, 2014, 09:15:05 AM »
thanks for your reply bababel, I am into my second week now of the increase and really very anxious and agoraphobic, do you get agoraphobic? she did not give me any benzos and to be honest I don't think I would of taken them anyway I would be scared of getting addicted. it is encouraging to know that your anxiety went after a couple of weeks, maybe I just need to stick it out a bit longer, it just feels I am never going to get better. 

Good luck with your increase, do you think you will increase further? I feel 100mg is too high but I will take anything to get better at the moment, especially as I have two young children to look after! It is really good to talk to someone going through the same as me and I really appreciate your replies.

I am not agoraphobic right now but when my anxiety is bad then I definitely don't want to leave the house. That was very true at the beginning of my Sertraline experience. It was so bad that I stayed home for a couple of weeks. I am much better now.

You won't become addicted to benzos. I didn't want to take them either but I found that it really helped me at night when my anxiety was at it's worst. I only took a small amount once a day (.25 Xanax) and then stopped taking them the day I felt better.  You will definitely feel better. You've made it this far in your treatment. Once the medication levels off in your system you will feel great relief.

I plan on staying at 75 mg as long as it works. If I get breakthrough anxiety again then I will definitely talk to my psychiatrist about going up to 100 mg. A friend of mine was at 100 mg for many years and she said it basically changed her life for the better. Whether you plan on staying at 100 or go down to 75 mg, you need to talk to your doctor first. Also, give it another week before you decide. In the meantime best of luck with your journey! I know how hard it can be and I almost gave up on Sertraline during the first few weeks, but I am so glad I stuck with it. I barely have any anxiety at all and when I do it is about 70% less than it used to be.  :yes:
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Offline Luisa1974

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Re: Increase of Sertraline(Zoloft)
« Reply #7 on: February 19, 2014, 02:54:44 AM »
Thanks insight for your reply, I am feeling awful today, I feel so sick and shaky, will this ease off? I have been on the increase for a week and a half now, have I got much longer to wait?

Bababel, thanks for your reply again! I feel like the medication is not working at the moment, how long did the increase take for it to work for you, sorry I am desperate for answers, is it worth calling my doctor again or should I give it another week to see what happens?
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Offline insights

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Re: Increase of Sertraline(Zoloft)
« Reply #8 on: February 19, 2014, 05:57:19 AM »
I have been on the increase for a week and a half now, have I got much longer to wait?

I don't know. It varies greatly depending on personal biology. Your side-effects experience when you first began taking sertraline can be a guide on what happens now, but it isn't always reliable unfortunately.

Ian
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NOTE: I'm not a doctor, and particularly not yours, so there may be factors I'm unaware of. Therefore all advice is of a general nature and you should consult your doctor before following any of it, especially before changing med doses.

Offline bababel

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Re: Increase of Sertraline(Zoloft)
« Reply #9 on: February 19, 2014, 10:41:42 AM »

Bababel, thanks for your reply again! I feel like the medication is not working at the moment, how long did the increase take for it to work for you, sorry I am desperate for answers, is it worth calling my doctor again or should I give it another week to see what happens?

Don't be sorry, I was desperate for answers too when I first started on the medication. The increase from 25 to 50 mg took at least two and a half weeks to start working. Probably more like three weeks, but I don't remember for sure. If you go back a page or two on the Medications and Therapy forum you can see the beginnings of my journey in a thread called "My Sertraline Journey". In it you will see that I went through something very similar to what you are going through.

Today I have an increase in anxiety and I think it is because I am on day 4 or 75 mg. If it gets really bad I will take a Xanax, but I am not too concerned about my symptoms since I know that they were bound to happen with the increase.

It does sound like you are suffering a lot. I would call your doctor and ask what you should do. He/she may suggest you go down to 75 mg temporarily before going back up to 100 mg, or they might tell you to stick with it for another week to see how you do. If they suggest you stick with the 100 mg, ask if they could give you a benzo in the meantime. I know you really don't want to take them but they will help you through this rough time. One a day can make a difference and you can stop taking them at any time without problems.

Good luck!!  :action-smiley-065:
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