I started taking Duloxetine (cymb) jan 18th at 20mg which is almost nothing...then titrated to 30mg 8 days ago. Should I be seeing any changes yet at all? My moods are still very mixed and kind of unstable, some days I feel calm and dont need Valium, while other days I feel jittery and on edge. Inconsistent energy levels too--why do I feel like I'm taking meth one day, then the next day (like today), I am lethargic and just stay in bed? I don't get this.