Xanax (Alprazolam) and Klonopin (Clonazepam) are both in the benzodiazepine classification.
Xanax is a short acting anxiolytic with a rapid onset of action, 90% of which is seen within an hour of taking the medication. Xanax is the most prescribed and the most misused benzodiazepine in the United States.
Klonopin, on the other hand, is a much longer acting anxiolytic, with a half life of 18-50 hours. It does have a more intermediate onset of action, taking between 1 to 4 hours to reach peak blood levels.
Benzodiazepines were always intended for short term use. Approximately a third of individuals treated with benzodiazepines for longer than four weeks develop a dependence on the drug and experience a withdrawal syndrome upon dose reduction.
Potatoes: Your increase in anxiety since starting Zoloft is unfortunate, but it is one of the main side effects of the start-up of a SSRI. When you start on a SSRI, serotonin levels are immediately increased, and this increases your anxiety. This side effect normally lasts several weeks before falling off to baseline levels. Patience, patience, patience, is what it takes for an anti-depressant to work.
The very best to all of you!... Chuck