Hello, I avoided all those side effects by taking 12.5mg(1/2 of a 25mg sertraline) for 2 weeks, then went up to 25mg and stayed there. It worked at a low dose for me, but I also started .5mg klonopin at night when I started the sertraline. I took sertraline for 2 yrs, and tapered off. Now I still remain on .5mg klonopin and am doing great. I had extreme anxiety, panic, gad, which led to a psychotic depression. I wish drs would let anxiety pts start the ssris at very low doses. We cant handle all that serotonin flooding our bodies. Good luck to u.