What do you think the chances are of the ssri doing some kind of damage to the frontal lobe of my brain? or a change or some sort?
Damage, not as far as I know. The only material I've seen on this issue is some nonsense from the Citizens Commission on Human Rights
, a front organization of the Church of Scientology which is opposed to psychiatry, I assume, for business reasons.
But antidepressants do trigger changes in the frontal lobes by increasing the connections
between the lobes and the Limbic system which regulates emotions. The Limbic system includes the amygdalas, two relatively primitive areas of the brain which trigger the automatic response to threats they perceives (people with damages amygdalas don't experience anxiety/fear). Among other things the frontal lobes apply intelligent processing to these threat reports, deciding which are and aren't real, so the better the communication between them the better. Basically, the amygdalas respond, for example, to you seeing a long slim round object out of the corner of your eye by activating the flight-or-fight response (via the hypothalamus and brainstem) and 'screaming' "snake, snake" at the frontal lobes. The frontal lobes then evaluate the data and may decide it's only a water hose and switch of the fear response.
i'm sure it's a rare issue but what do you think? am i just causing myself fear and it's likely the ssri issue that you tell me?
Not only is it not an issue, but SSRIs are used to treat
the symptoms of frontotemporal dementia
, a neurodegenerative disease of the frontal lobes due to cell loss.
SSRIs have now been available for over 25 years and other serotonergic antidepressants for over 50, with some having taken antidepressants continually for nearly all that time. I've been on them pretty much continually for 27 years at doses well above the recommended maximum. If their long-term used damaged the brain it would have become very evident by now.