No, not really. I used to be freaked out about the whole 2012 thing a few years ago, but I thought a lot about it, and feel fine about it now. I'll be with my boyfriend, so even if something were to happen, at least I would be with someone I love.
In all seriousness though, nothing's going to happen. There have been SO many times when it was predicted that the world was going to end, and it did not. Don't worry. :) If you're really scared, find someone to be with that night. A significant other, a friend, or family member could help you feel better.