What can cause a lot of headaches and neck pressure? Honestly I assume it would be a brain tumor, that's what I thought but I have no idea how likely it is. I have a headache and a lot of neck pressure and strange feelings throughout my body. It could be stress but Im so sure it's something worse. Is neck pressure with accompanying headache several times a week something to worry about? I've had strange feelings like a pressure/pain in my right leg for a bit today but im not sure if it's serious or not. Im terrified this is something serious. And if it doesn't sound serious, what would make you think it was? What else would have to happen for it to be serious?