Today is day 26, I think. (Day 19 since I started taking a theraputic dose, 10 mg) and I have good days and bad. I haven't seen a significant improvement overall, at least not yet. I am extremely nauseated in the mornings and it lingers a bit but the headaches have stopped for the most part. I am not sure if you feel the positive affects all of a sudden or it is a gradual thing? I am trying to remain patient...other people's feedback is so helpful and is much appreciated.