I'm wondering if you guys might have any experience or advice on beta blockers. I'm weighing the decision to replace my daily dosing of guanfacine with a beta blocker, mainly because I have health anxiety fears and guanfacine isn't medically recommended in a combination with mirtazapine. I'm giving the Remeron a 2nd try (after having gained a few pounds the first time on it), and I am noticing that it is helping both my anxiety and depression. However, if you go to any drug-interactions website, they will list those two drugs as having a potentially dangerous hypertensive interaction...my psychiatrist has told me it's an unlikely circumstance given that I'm young and have an otherwise healthy BP range, and that it's more or less uncommonly seen empirically in the medical profession. However, I have a difficult time merely realizing that this interaction exists, because I dwell on it. Ultimately, this potential for an interaction is detracting from the psychological therapeutic potential of these medications.
I am not yet throwing my hands up on the guanfacine (Tenex), but I have an appt. with my psychiatrist later this week and I would just like to do some research on some alternative options. Keep in mind, I'm currently on an anti-hypertensive med because for me it helps with the source of my anxiety, which is very much related to the involuntary physiological sensations (higher HR, BP, etc.) that are accompanied by anxious moments.
I suppose what I'm asking is which beta blockers have less CNS side effects, particularly the ones which do not cross the Blood Brain Barrier?