I wake up in the middle of the night or in the morning with certain fingers feeling numb like they fell asleep and I have to shake them to get the blood flowing again. This happens mostly when I sleep on my back. I do have some back/neck issues. A Chiropractor told me....I might not have this information correct as it's been a while since he told me this, but if the two outer fingers go numb it may be related to a nerve in the neck and the other fingers would be carpal tunnel related? But don't quote me on this. In other words, your issue could just be a pinched nerve or something less serious than MS. I also wake up with my feet going numb at times especially if I sleep on my side, as my left ankle presses against my right foot. I see an advanced Chiropractor who wants me to see this chiropractor\neurologist to get evaluated. I know I have some issues with my lower back. I might have some pressed nerves down there. I also had spinal surgery (disc replacement) on my neck (C5-C6). So, I definatley have some structural issues.