Though I cannot relate to the slurred speech, I've had the tightness in my leg all day long. I've been stressing over MS over a week now. Ever since I looked up the symptoms I've had tingling, twitching, lump in the throat, the whole 9 yards. We just have to remember that these are all symptoms of stress and anxiety too. See your Dr. to ease your mind. I'm excited and nervous for my appointment tomorrow morning. If you started having these symptoms AFTER you looked them up, it's probably not a coincidence. We can create these by worrying about them, I know I have.