Right now there isn't a cure in the permanent sense AFAIK, but one can be anxiety free for many years between episodes, as I have been, albeit usually on medication. One of the more troubling things to me is that sometimes medications may fail to keep working forever, and that is frustrating because it means finding something else that hopefully will work better. We really need serious research into AD "poopout" and what can reverse it, for example can a med that worked years ago work again so that you could just cycle back and forth if needed (I can find no research and very little anecdotal evidence on the net on this question). Meanwhile there is great hope especially for the younger folks in the sense that research continues to move forward, so besides new medicines coming out, there is stuff going on with magnetic stimulation and electrical stimulation (not ECT, much milder stuff) that I think might reveal better treatment methods in the future. One of the things I like about the idea of treating the brain itself is that it is a brain disorder, the meds often target receptors all over the body which accounts for the various side effects experienced--so a targeted therapy if possible would be better. And finally the genetics of this will be sorted out, likely within a decade in my estimation, and that does two things--provide more targets for drug therapy and possibly one day allow genetic engineering to devise a cure (difficult technical issues will remain with that though for some time) by replacing a faulty gene with a better one. We still need to fight it with CBT or whatever therapy and for those lucky ones for whom this is enough that is fantastic, but for many others we will need some more medical breakthroughs to get a cure for it. This may sound bizarre, but if they had a for sure surgical cure for it that was no more dangerous than other surgeries, I'd be first in the line, that's how bad I would want this anxiety/depression demon out of my life for good. I can remember the years before it began, and the years of freedom inbetween (though after your first panic attack you will never forget that, its like a trauma unto itself), so I know life is good when the demon is caged. I look forward to the time when future generations will not have to know the struggles we have had to go thru with this, so I do believe there will be a cure one day.