I have remained on the unmedicated side of things for quite some time (I could be diagnosed as GAD) and am finding some relief with herbal supplements, a B complex and fish oil. I take a small dose of St. John's wort in the am, along with tinctures of lemon balm, California poppy and skullcap as needed. For sleep, I have a ritual of drinking a cup of chamomile tea. I know it sounds "weak" but it really works to help make me sleepy. Spirituality, yoga, music, EMDR (trauma therapy) and CBT have helped the most.
And oddly, aromatherapy does help. My therapist once gave this patch with various oils in it that were quite soothing.
I have just read some powerfully convincing research about CBD (cannabidiol) being very effective for anxiety. It is the non-THC component of the hemp plant. It's legal in the US because it doesn't get you high. I ordered some and am waiting for it to come in the mail. If I find it effective, I will make a thread about it.