Sexual side effects that may occur in SSRIs and Trycyclics have been reported to be lower for users on Brintellix.
Just about every antidepressant after the first one has made this claim and with only two or three exceptions it has turned out to be male bovine manure.
Is anyone familiar with this newly approved FDA medication? Would you know why it's not deemed a SSRI/SNRI? Since it is a unique antidepressant in comparison to the major three antidepressant groups (SSRIs, Trycyclics, MAIOs), is it classified as an atypical antidepressant?
Lundbeck and Takeda and pushing the atypical angle, but it looks like a SSRI to me. They claim it is different because in addition to blocking serotonin transporters it is affects 5-HT1a, 5-HT1b, 5-HT1d, 5-HT3a and 5-HT7 receptors, however, they also acknowledge that they have no idea what effects this has, so take it all with a large dollop of salt for now. The only real novel aspect is the targeting of the 5-HT3a and 5-HT7 receptors.
And for users who have complained that SSRIs do not work for them, could they possibly benefit from Brintellix? (In terms of that question, I assume a user would have to try it in order to find out.)
Possibly. The more arrows in the quiver the more chances you have of hitting the bullseye.
Although I will probably never have plans to get off my medication, Zoloft (Setraline), I'm still curious if Brintellix would also work for the treatment of my anxiety disorder, since some antidepressants (like Setraline) tend to work better for anxiety than depression.
I certainly would be waiting several years before contemplating switching. Drug trials results are one thing (and those for vortioxetine were fairly ordinary), but they don't always translate that well in the field where the patients aren't carefully selected.