I realize (no pun intended) that this is a very old thread, however I have been thinking VERY similar to what Queezus described. For example if you were feeling this way you would be sitting here questioning if I am real or just a creation of some "imagination" or chemicals in the universe basically. I have been depressed for a few years, diagnosed with depressive disorder NOS and am very socially anxious, though not diagnosed with social anxiety disorder. I also have occasional spells of anxiety. A few days ago I woke up with what I suppose was my first panic attack, tingling and numbness in the arms and mouth, and my hands felt extremely weird when I touched things, like sliding my hand across my shorts felt like my hand was "lagging" sort of like when in water, the sensations themselves were definitely more horrific than the emotions that caused them. Ever since then I was worried about having more panic attacks, which I have been waking up every morning with the numb/tingling, slightly less intense though. But about 3 days ago I started questioning everything, from the ground up. The questioning if I am the only consciousness has made my anxiety worse and made me feel very detached and alone. I've questioned reality and life in itself, everything including physical feelings and sensations, to emotions and tastes and sounds. All in all a "maybe this isn't real" feeling would probably make anyone feel depressed. It's seeming to get a little less intense, I have bouts where I start convincing myself that it's definitely not true and I'm ok, but then later the same day I'll go back to feeling totally dreadful, I currently am having trouble eating from it and actually threw up from forcing myself to eat. It's like I start thinking about it, and it's a hard concept to think about(which explains why not many people do) and once I think so far I hit that one spot where everything feels fake and I start to feel very anxious and dreadful. Also having trouble getting to sleep, and having vivid and strange dreams, not quite nightmares. Assuming I am real and all of you are real, our minds are very very powerful, but nobody can truly know the answers to these questions, it really seems like if it is indeed in my(or our) heads, that it's something I will just have to give time to move on or forget about. I am currently going to the doctor August 2nd for a physical in which my therapist that I'm no longer going to told me I could ask about medications for my depression. However I am thinking about seeing if I can get to the doctor sooner, as I am sure an anti-anxiety medication would help me get out of this rut, or at least help me eat/sleep better until I do.